Hand & WristMeta-analysis

A Comparative Analysis of Surgical Treatment for First Carpometacarpal Osteoarthritis: A Systematic Review and Pooled Analysis of Randomised Controlled Trials

Hand · 12 Oct 2026

Rigour70/100
Clinical53/100
Impact†49/100

† Impact is the editorial-priority score. All scores are out of 100. Clinical is a stored clinical-importance score from the earlier method; it has not been recalculated.

Why it matters

Trapeziectomy-based procedures are the classic operation for thumb CMC arthritis, and dual-mobility prostheses are a newer option that may speed early recovery, but any long-term trade-off in revision risk remains unknown.

The evidence

This review pooled 7 randomised trials (409 hands) of surgery for thumb base (first carpometacarpal) arthritis and grouped the treatment arms into soft-tissue reconstruction (such as LRTI), trapeziectomy without reconstruction, and dual-mobility joint replacement. At 3 months the implant arms had the largest average drop in VAS pain (about 6.05 points, versus 3.52 for reconstruction and 2.86 for non-reconstruction). By 12 months pain improvement was similar across groups (5.98 to 6.54 points). These were descriptive within-group averages, not formal between-group comparisons.

A coherent primary effect estimate is unavailable. Clinical relevance does not estimate treatment benefit.

Why this rigour score?

Systematic reviewDesign starting point: 50.4

70/ 100

Raised the score

  • Pools randomised trials+5.1
  • Compared against current standard of care+3.4

Lowered the score

    No negative adjustments recorded.

    Methods at a glance

    Recorded assessment
    • Comprehensive literature searchMet
    • Risk of bias assessedMet
    • Bias considered in synthesisMet
    • Publication bias assessedNot met
    • Study exclusions justifiedMet
    • Prospective registrationNot reported

    Not reported does not mean not done. Checks have different weights; this is not a count of boxes ticked.

    See the full score breakdown
    Study design starting point
    50.4
    Compared against current standard of care
    +3.4
    Pools randomised trials
    +5.1
    Comprehensive literature search
    +3.4
    Risk of bias assessed in the included studies
    +3.4
    Risk of bias carried into the synthesis
    +2.5
    Excluded studies listed and justified
    +1.7
    Final rigour score rounded
    70 / 100

    Study design sets the starting point and a ceiling of 88. Recorded methods then adjust the score. Points are shown to one decimal place; the final score uses unrounded values.

    Checklist from the stored appraisal. “Not met” describes the recorded criterion; it does not always produce a deduction. This overview supports reading the full study.

    For journal club

    1.For a 60-year-old manual worker with Eaton stage III thumb CMC arthritis, how would you weigh a possibly faster early recovery with a dual-mobility implant against the proven long-term durability of trapeziectomy with or without LRTI?

    2.How should you counsel a patient choosing simple trapeziectomy about the expected temporary dip in grip strength in the first 3 months and the likely similar pain relief by 1 year?

    Original publication title

    A Comparative Analysis of Surgical Treatment for First Carpometacarpal Osteoarthritis: A Systematic Review and Pooled Analysis of Randomized Controlled Trials

    Read original paper