SpineMeta-analysis

Supine ALIF versus Lateral-Decubitus OLIF for Degenerative Lumbar Disease

Spine · 15 Oct 2026

Rigour37/100
Clinical49/100
Impact†48/100

† Impact is the editorial-priority score. All scores are out of 100. Clinical is a stored clinical-importance score from the earlier method; it has not been recalculated.

Why it matters

ALIF and OLIF are both common anterior-column fusion approaches, so knowing that neither shows a clear complication or patient-reported outcome advantage in retrospective data helps frame approach selection and patient counselling.

The evidence

This meta-analysis pooled 13 retrospective studies (1,432 patients) that directly compared supine anterior lumbar interbody fusion (ALIF) with lateral-decubitus oblique lumbar interbody fusion (OLIF) for degenerative lumbar disease. OLIF was associated with about a one-day shorter hospital stay (mean difference -0.87 days, 95% CI -1.47 to -0.26) and greater reduction in sagittal vertical axis. Operative time and blood loss favoured OLIF only after an outlier study was removed, and complications and patient-reported pain and disability did not differ.

A coherent primary effect estimate is unavailable. Clinical relevance does not estimate treatment benefit.

Why this rigour score?

Meta-analysis of observational studiesDesign starting point: 37.4

37/ 100

Raised the score

  • Compared against current standard of care+3.4
  • Comprehensive literature search+3.4

Lowered the score

  • Pools observational studies−6.8
  • No assessment of publication bias across 13 studies−6.8

Methods at a glance

Recorded assessment
  • Comprehensive literature searchMet
  • Risk of bias assessedMet
  • Bias considered in synthesisMet
  • Publication bias assessedNot met
  • Study exclusions justifiedNot met
  • Prospective registrationNot reported

Not reported does not mean not done. Checks have different weights; this is not a count of boxes ticked.

See the full score breakdown
Study design starting point
37.4
Compared against current standard of care
+3.4
Pools observational studies
−6.8
Comprehensive literature search
+3.4
Risk of bias assessed in the included studies
+3.4
Risk of bias carried into the synthesis
+2.5
No assessment of publication bias across 13 studies
−6.8
Final rigour score rounded
37 / 100

Study design sets the starting point and a ceiling of 78. Recorded methods then adjust the score. Points are shown to one decimal place; the final score uses unrounded values.

Checklist from the stored appraisal. “Not met” describes the recorded criterion; it does not always produce a deduction. This overview supports reading the full study.

For journal club

1.For an older patient with significant comorbidities who needs an L5-S1 interbody fusion, how would you weigh OLIF's possibly shorter stay against the reported level-specific vascular risk at L5-S1?

2.If a patient's main goal is pain and disability relief rather than global alignment correction, does a greater SVA reduction with OLIF justify choosing it over ALIF?

Original publication title

Supine ALIF versus Lateral-Decubitus OLIF for Degenerative Lumbar Disease

Read original paper