Bone & Joint Open IF 2.8 Jul 21 2026 LoE I Full text read
Comparative efficacy of analgesic techniques in total hip arthroplasty
This network meta-analysis pooled 112 randomized trials comparing 23 different regional analgesic techniques (nerve blocks, periarticular injection, intrathecal morphine, and combinations) against placebo in patients undergoing total hip arthroplasty. On the primary outcome, postoperative day 1 pain score, several techniques reached statistical significance versus placebo but none crossed the pre-defined MCID of 1.86 points on the VAS, meaning no technique produced a pain reduction patients would actually notice; secondary analyses found intrathecal morphine and iliopsoas block plus periarticular injection reduced opioid use, and intrathecal morphine and pericapsular nerve group (PENG) block shortened hospital stay.
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Why it mattersThis challenges the assumption, embedded in current PROSPECT guidelines, that specific regional blocks meaningfully reduce pain after hip arthroplasty, and instead points clinicians toward opioid-sparing and discharge-related benefits rather than pain control itself.
Rigor × clinical importance